The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2023

Filed:

Jul. 07, 2020
Applicant:

Stokes Bio Ltd., Limerick, IE;

Inventors:

Mark Davies, Limerick, IE;

Tara Dalton, Limerick, IE;

Kieran Curran, Limerick, IE;

Assignee:

STOKES BIO LTD., Limerick, IE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); B01F 13/00 (2006.01); B01F 15/02 (2006.01); F17D 1/08 (2006.01); C12Q 1/686 (2018.01); B01F 35/71 (2022.01); B01F 33/302 (2022.01); B01F 101/23 (2022.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502784 (2013.01); B01F 33/3021 (2022.01); B01F 35/7172 (2022.01); B01L 3/502715 (2013.01); B01L 3/502746 (2013.01); C12Q 1/686 (2013.01); F17D 1/08 (2013.01); B01F 35/71 (2022.01); B01F 2101/23 (2022.01); B01L 3/5025 (2013.01); B01L 7/525 (2013.01); B01L 2200/0673 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/0838 (2013.01); B01L 2400/0478 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0633 (2013.01); B01L 2400/082 (2013.01); Y10T 137/87676 (2015.04); Y10T 436/117497 (2015.01); Y10T 436/118339 (2015.01); Y10T 436/2575 (2015.01);
Abstract

A system for processing a biological sample includes a substrate comprising a plurality of wells and a plurality of flow channels. The system further includes a flow control system comprising a manifold having a plurality of ports configured to fluidically couple to the plurality of wells, and one or more containment structures configured to contain carrier fluid and fluidically couple to the ports. The flow control system further includes a cradle configured to removably receive the substrate. The flow control system is configured to transmit pressure differential, via the manifold, to the plurality of wells so as to cause a plurality of sample volumes held by at least some wells of the plurality of wells to flow through respective flow channels and cause the carrier fluid to flow through the flow channels and form a plurality of droplets of the plurality of sample volumes separated by the carrier fluid.


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