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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11771807 B1

PDFFull Text
Date of Patent:
Oct. 03, 2023

Filed:

Jul. 18, 2019

Nanofiber-hydrogel composites for cell and tissue delivery

Applicant:

The Johns Hopkins University, Baltimore, MD (US);

Inventors:

Sashank Reddy, Baltimore, MD (US);

Russell Martin, Baltimore, MD (US);

Xiaowei Li, Towson, MD (US);

Calvin Chang, Baltimore, MD (US);

Kevin Colbert, Baltimore, MD (US);

Hai-Quan Mao, Baltimore, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:

Fox Rothschild LLP

Primary Examiner:

Anna R Falkowitz

Int. Cl.
CPC ...
A61L 27/58 (2006.01); A61L 27/54 (2006.01); A61L 27/20 (2006.01); A61L 27/18 (2006.01); A61L 27/44 (2006.01); A61L 27/38 (2006.01); A61L 27/52 (2006.01); A61M 5/19 (2006.01); A61L 27/48 (2006.01); A61L 27/56 (2006.01); B82Y 5/00 (2011.01); B82Y 30/00 (2011.01); B82Y 40/00 (2011.01);
U.S. Cl.
CPC ...
A61L 27/58 (2013.01); A61L 27/18 (2013.01); A61L 27/20 (2013.01); A61L 27/3808 (2013.01); A61L 27/3834 (2013.01); A61L 27/3895 (2013.01); A61L 27/44 (2013.01); A61L 27/48 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61M 5/19 (2013.01); A61L 2300/412 (2013.01); A61L 2300/414 (2013.01); A61L 2300/602 (2013.01); A61L 2300/604 (2013.01); A61L 2300/622 (2013.01); A61L 2400/06 (2013.01); A61L 2400/12 (2013.01); A61L 2430/34 (2013.01); A61M 2202/08 (2013.01); A61M 2202/09 (2013.01); B82Y 5/00 (2013.01); B82Y 30/00 (2013.01); B82Y 40/00 (2013.01);
Abstract

A soft tissue device can incorporate a composite material comprising a gel and at least one nanostructure disposed within the gel. A soft tissue device can further incorporate biologically active materials such as cells, tissues. A method for healing a soft tissue defect while promoting soft tissue regeneration can include applying a soft tissue device to a soft tissue defect, wherein the composite material includes a gel and a nanostructure disposed within the gel. A method for manufacturing a soft tissue device for use in healing soft tissue defects can include providing a gel, disposing nanofibers within the gel, and a biologically active material.

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