The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2023

Filed:

Jun. 27, 2022
Applicant:

Sealantium Medical Ltd., Rosh HaAyin, IL;

Inventors:

Orgad Laub, Tel Aviv, IL;

Eran Cohen, Hod Hasharon, IL;

Yotam Schwartz, Petah Tiqwa, IL;

Assignee:

SEALANTIUM MEDICAL LTD, Rosh Haayin, IL;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61L 24/04 (2006.01); A61K 38/36 (2006.01); A61K 38/48 (2006.01); B29D 7/01 (2006.01); B29L 31/00 (2006.01); B29K 75/00 (2006.01);
U.S. Cl.
CPC ...
A61L 24/043 (2013.01); A61K 38/363 (2013.01); A61K 38/4833 (2013.01); B29D 7/01 (2013.01); A61L 2300/252 (2013.01); A61L 2400/04 (2013.01); B29K 2075/00 (2013.01); B29K 2995/0056 (2013.01); B29L 2031/753 (2013.01);
Abstract

A method of production of a tissue sealing patch is disclosed. The method comprises applying a vacuum to a heated work surface; applying a solution of a biocompatible polyurethane polymer to the work surface and spreading it over the work surface with a polymer blade; evaporating the solvent; heating the work surface above the softening temperature of the polymer; spreading powdered tissue sealant material over the polymer film; incorporating the tissue sealant material to a depth of 20-60 μm in the film by pressing on a release sheet placed over the powder and polymer film; removing the release sheet from the adhesive patch material; releasing the vacuum; cooling said work surface; and removing the adhesive patch material from said work surface. The biocompatible polymer preferably comprises PEG-caprolactone-lactic acid units connected by urethane linkages, the PEG having a molecular weight of 3000-3500 amu, and a CL:LA:PEG ratio of 34:2:1.


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