The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 03, 2023
Filed:
Feb. 28, 2019
University of Washington, Seattle, WA (US);
Neil King, Seattle, WA (US);
David Baker, Seattle, WA (US);
Lance Stewart, Seattle, WA (US);
Brooke Fiala, Seattle, WA (US);
Daniel Ellis, Seattle, WA (US);
Lauren Carter, Seattle, WA (US);
Rashmi Ravichandran, Seattle, WA (US);
George Ueda, Seattle, WA (US);
Jorge Fallas, Seattle, WA (US);
Una Nattermann, Seattle, WA (US);
University of Washington, Seattle, WA (US);
Abstract
Nanostructures and nanostructure-based vaccines that display antigens capable of eliciting immune responses to infectious agents such as bacteria, viruses, and pathogens are provided. Some vaccines are useful for preventing or decreasing the severity of infection with an infectious agent, including, for example and without limitation, lyme disease, pertussis, herpes virus, orthomyxovirus, paramyxovirus, pneumovirus, filovirus, flavivirus, reovirus, retrovirus, meningococcus, or malaria. The antigens may be attached to the core of the nanostructure either non-covalently or covalently, including as a fusion protein or by other means. Multimeric antigens may optionally be displayed along a symmetry axis of the nanostructure. Also provided are proteins and nucleic acid molecules encoding such proteins, vaccine compositions, and methods of administration.