The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2023

Filed:

Apr. 28, 2022
Applicant:

Restore Vision Inc., Tokyo, JP;

Inventors:

Toshihide Kurihara, Tokyo, JP;

Yusaku Katada, Tokyo, JP;

Kazuo Tsubota, Tokyo, JP;

Hideki Kandori, Nagoya, JP;

Assignee:

Restore Vision Inc., Tokyo, JP;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61P 27/02 (2006.01); C07K 14/705 (2006.01); C07K 19/00 (2006.01); C12N 5/10 (2006.01); C12N 15/62 (2006.01); C12N 15/63 (2006.01); A61K 38/16 (2006.01); A61K 31/7088 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
A61K 38/16 (2013.01); A61K 31/7088 (2013.01); A61K 38/177 (2013.01); A61P 27/02 (2018.01); C07K 14/705 (2013.01); C07K 19/00 (2013.01); C12N 5/10 (2013.01); C12N 15/62 (2013.01); C12N 15/63 (2013.01); C12N 15/86 (2013.01); C07K 2319/00 (2013.01);
Abstract

Provided are: a nucleic acid including a nucleic acid sequence encoding a chimeric protein including at least part of an ion-transporting receptor rhodopsin and at least part of a G protein-coupled receptor rhodopsin and a nucleic acid sequence encoding a signal sequence; and a nucleic acid including a nucleic acid sequence encoding a chimeric protein including at least part of an ion channeling receptor rhodopsin and at least part of a G protein-coupled receptor rhodopsin; and a nucleic acid construct including the nucleic acid sequences. The use of the nucleic acids or nucleic acid constructs prevents and suppresses the progress of retinal diseases, and enhances the visual cognitive behavioral function and visual function.


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