The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2023

Filed:

Jun. 18, 2018
Applicants:

Vanderbilt University, Nashville, TN (US);

The United States As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Jack Jacek Hawiger, Nashville, TN (US);

Jozef Zienkiewicz, Nashville, TN (US);

Ruth Ann Veach, Brentwood, TN (US);

Yan Liu, Nashville, TN (US);

Lukasz Wylezinski, Nashville, TN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01); A61P 31/04 (2006.01);
U.S. Cl.
CPC ...
A61K 38/16 (2013.01); A61P 31/04 (2018.01);
Abstract

Disclosed are compositions and methods for treating microbial inflammation including its end-stage sepsis and conditions associated with the microbial inflammation such as thrombocytopenia and hypoglycogenemia. In one aspect, the compositions and methods disclosed herein can also be used to enhance clearance of microbes from infected tissues, organs, or systems in a subject. Also disclosed herein are compositions and methods for reducing levels of stress responsible transcription factors and metabolic transcription factors in a cell in a subject with microbial inflammation.


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