The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 03, 2023

Filed:

Dec. 09, 2021
Applicant:

Cerion, Llc, Rochester, NY (US);

Inventor:

Eric Leslie Bell, Webster, NY (US);

Assignee:

Cerion, LLC, Rochester, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/51 (2006.01); A61K 9/10 (2006.01); A61K 33/24 (2019.01); A61K 31/197 (2006.01); A61K 47/18 (2017.01); A61K 47/12 (2006.01); A61K 9/14 (2006.01); A61K 9/16 (2006.01); A61K 33/244 (2019.01); A61K 33/243 (2019.01); F41C 33/00 (2006.01); F41C 33/04 (2006.01); A61K 9/00 (2006.01); F41C 33/02 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5123 (2013.01); A61K 9/10 (2013.01); A61K 9/14 (2013.01); A61K 9/1688 (2013.01); A61K 9/5192 (2013.01); A61K 31/197 (2013.01); A61K 33/24 (2013.01); A61K 33/243 (2019.01); A61K 33/244 (2019.01); A61K 47/12 (2013.01); A61K 47/183 (2013.01); F41C 33/008 (2013.01); F41C 33/048 (2013.01); A45F 2200/0591 (2013.01); A61K 9/0019 (2013.01); F41C 33/0245 (2013.01); F41C 33/041 (2013.01);
Abstract

A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, ethylenediaminedisuccinic acid, an oxidant, water, and optionally citric acid, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of cerium oxide nanoparticles. Biocompatible nanoparticles comprised of cerium oxide, ethylenediaminedisuccinic acid, and optionally citric acid, are described. An increase in catalase-like enzyme activity is demonstrated by cerium oxide nanoparticles prepared with citric acid and ethylenediaminedisuccinic acid.


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