The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2023
Filed:
Jun. 06, 2017
Max-planck-gesellschaft Zur Förderung Der Wissenschaften E.v., Munich, DE;
Medizinische Universität Wien, Vienna, AT;
Julia Tornack, Berlin, DE;
Stephen Reece, Brentwood, GB;
Fritz Melchers, Grenzach, DE;
Stefan H. E. Kaufmann, Berlin, DE;
Wolfgang Bauer, Vienna, AT;
Georg Stingl, Vienna, AT;
Max-Planck-Gesellschaft, Munich, DE;
Medizinische Universität Wien, Wien, DE;
Abstract
The present invention relates to a method for the in vitro detection of a latent tuberculosis infection (LTBI) in a subject, wherein said method comprises determining at least one nucleotide sequence and/or at least one polypeptide of(Mtb) in a blood cell population of said subject, and wherein the presence of said at least one nucleotide sequence and/or said at least one polypeptide is indicative for said latent tuberculosis infection. In particular, the blood cell population is enriched for hematopoietic stem cells. The invention also relates to a pharmaceutical composition for use in the treatment of the LTBI in the subject, wherein it is determined if the nucleotide sequence and/or the polypeptide of Mtb is/are present in the blood cell population. Further, the invention relates to kits for carrying out the methods of the invention. The invention also relates to the use of the kits.