The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2023
Filed:
Dec. 07, 2018
Applicant:
Massachusetts Institute of Technology, Cambridge, MA (US);
Inventors:
J. Christopher Love, Somerville, MA (US);
Todd Michael Gierahn, Brookline, MA (US);
Alexander K. Shalek, Lexington, MA (US);
Marc Havens Wadsworth, Somerville, MA (US);
Travis K. Hughes, Cambridge, MA (US);
Assignee:
Massachusetts Institute of Technology, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6874 (2018.01); C12Q 1/6806 (2018.01); C12N 15/10 (2006.01); G03F 7/20 (2006.01); B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6874 (2013.01); B01L 3/5085 (2013.01); C12N 15/1068 (2013.01); C12N 15/1093 (2013.01); C12N 15/1096 (2013.01); C12Q 1/6806 (2013.01); G03F 7/2014 (2013.01); B01L 2200/0647 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0829 (2013.01); B01L 2300/0851 (2013.01);
Abstract
Modifications to both hardware and enzymatic reactions used in single cell analyses such as but not limited to Seq-well that enable significant increases in the yield of transcripts per cell, portability and ease of use, increased scalability of the assay, and linkage of transcript information to other measurements made in the picowell arrays are disclosed.