The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 2023

Filed:

Dec. 30, 2020
Applicant:

Akonni Biosystems, Inc., Frederick, MD (US);

Inventors:

Christopher G. Cooney, Ellicott City, MD (US);

Rebecca Holmberg, Rockville, MD (US);

Phillip Belgrader, Livermore, CA (US);

Peter Qiang Qu, New Market, MD (US);

Assignee:

AKONNI BIOSYSTEMS, INC., Frederick, MD (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6806 (2018.01); G01N 35/10 (2006.01); B01L 3/00 (2006.01); B01L 9/06 (2006.01); G01N 35/00 (2006.01); C12N 1/06 (2006.01); C12N 13/00 (2006.01); C12Q 1/689 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01); B01L 3/5082 (2013.01); B01L 3/52 (2013.01); B01L 9/06 (2013.01); C12N 1/066 (2013.01); C12N 13/00 (2013.01); C12Q 1/689 (2013.01); G01N 35/0099 (2013.01); G01N 35/1002 (2013.01); B01L 2300/0609 (2013.01); B01L 2300/0832 (2013.01);
Abstract

An integrated sample purification system includes a housing, a sample container rack, a filter holder, and a cylindrical magnet. The sample container rack and the filter device holder are disposed in the housing. The sample container rack is configured to hold one or more sample containers, the filter device holder is configured to hold one or more filter devices. The cylindrical magnet is adjacent to and external to the sample container rack, and is rotated about a central, longitudinal axis of the magnet by an electric motor disposed in the housing to lyse cells. Molecules of interest in the lysed cells are purified using filters that bind specifically to the molecules of interest. The system is readily amenable to automation and rapid purification and analysis of molecules of interest, such as nucleic acids and proteins.


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