The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2023
Filed:
Jun. 17, 2021
Applicant:
Modernatx, Inc., Cambridge, MA (US);
Inventors:
Amy E. Rabideau, Waltham, MA (US);
Athanasios Dousis, Somerville, MA (US);
Kanchana Ravichandran, Cambridge, MA (US);
Elissa Hobert, Cambridge, MA (US);
Assignee:
ModernaTX, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/00 (2006.01); C12N 9/12 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
C12P 19/34 (2013.01); C12N 9/1247 (2013.01); C12Y 207/11023 (2013.01);
Abstract
The present disclosure provides, in some aspects, variant RNA polymerases, the use of which increases transcription efficiency while reducing the number of double-stranded RNA contaminates and run-on transcripts produced during an in vitro transcription reaction.