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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11767526 B1

PDFFull Text
Date of Patent:
Sep. 26, 2023

Filed:

Jan. 21, 2020

Treatment of ophthalmic conditions with angiopoietin-like 7 (angptl7) inhibitors

Applicant:

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Inventors:

Kavita Praveen, Tarrytown, NY (US);

Claudia Schurmann, Tarrytown, NY (US);

Lauren Gurski, Tarrytown, NY (US);

Tanya Teslovich Dostal, Tarrytown, NY (US);

Goncalo Abecasis, Tarrytown, NY (US);

Aris Baras, Tarrytown, NY (US);

Giovanni Coppola, Tarrytown, NY (US);

Carmelo Romano, Tarrytown, NY (US);

Assignee:

Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);

Attorney:

Armstrong Teasdale LLP

Primary Examiner:

Dana H Shin

Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 9/22 (2006.01); C12Q 1/6883 (2018.01); C12N 15/113 (2010.01); C07K 14/515 (2006.01); A61K 31/713 (2006.01); A61K 48/00 (2006.01); A61P 27/02 (2006.01); A61P 27/06 (2006.01);
U.S. Cl.
CPC ...
C12N 15/11 (2013.01); A61K 31/713 (2013.01); A61K 48/005 (2013.01); C07K 14/515 (2013.01); C12N 9/22 (2013.01); C12N 15/111 (2013.01); C12N 15/1136 (2013.01); C12Q 1/6883 (2013.01); A61P 27/02 (2018.01); A61P 27/06 (2018.01); C12N 2310/14 (2013.01); C12N 2310/20 (2017.05); C12N 2800/80 (2013.01); C12Q 2600/106 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/158 (2013.01); C12Q 2600/178 (2013.01);
Abstract

The present disclosure provides methods of treating patients having an ophthalmic condition, methods of identifying subjects having an increased risk of developing an ophthalmic condition, methods of detecting human angiopoietin like 7 (ANGPTL7) variant nucleic acid molecules and variant polypeptides, and ANGPTL7 variant nucleic acid molecules and variant polypeptides.

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