The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2023
Filed:
Jun. 05, 2019
Applicant:
Promega Corporation, Madison, WI (US);
Inventors:
Michael Killoran, Madison, WI (US);
Ce Shi, Madison, WI (US);
Mary Hall, Madison, WI (US);
Lance P. Encell, Madison, WI (US);
Thomas Kirkland, Madison, WI (US);
Assignee:
Promega Corporation, Madison, WI (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2006.01); G01N 21/76 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0069 (2013.01); C12Y 113/12 (2013.01); G01N 21/763 (2013.01);
Abstract
Provided herein are enhanced luciferase enzymes for use with thermostable luciferin analogs for bioluminescent assays. In particular, the present disclosure provides compositions, assays, and methods for performing a bioluminescent assay using enhanced, high-activity luciferase enzymes compatible with thermostable luciferins, such as 5,5-disubstituted luciferin analogs.