The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 2023

Filed:

Jul. 13, 2018
Applicant:

Corning Incorporated, Corning, NY (US);

Inventors:

Gregory Roger Martin, Acton, ME (US);

Ana Maria Del Pilar Pardo, Portsmouth, NH (US);

Michael Kurt Schaefer, Gorham, ME (US);

Allison Jean Tanner, Portsmouth, NH (US);

Assignee:

CORNING INCORPORATED, Corning, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 3/06 (2006.01); B01L 3/00 (2006.01); C12M 1/24 (2006.01); C12M 1/04 (2006.01); C12M 1/00 (2006.01);
U.S. Cl.
CPC ...
C12M 23/16 (2013.01); B01L 3/502715 (2013.01); C12M 23/08 (2013.01); C12M 23/24 (2013.01); C12M 29/04 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/12 (2013.01);
Abstract

A cell culture vessel () includes a wall including an inner surface defining a cell culture chamber of the vessel. A substrate () of non-porous material is positioned in the cell culture chamber between a first region of the cell culture chamber and a second region of the cell culture chamber. The substrate includes a plurality of microcavities (), each microcavity of the plurality of microcavities includes a concave surface defining a well and an opening, the concave surface of each microcavity includes at least one aperture including a dimension less than or equal to about 15 microns defining a path from the well to the second region. A cell culture vessel including a substrate including a plurality of microcavities and a layer of porous material is also provided. Methods of culturing cells in the cell culture vessel are also provided.


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