The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 2023

Filed:

Nov. 25, 2020
Applicant:

Praxis Precision Medicines, Inc., Cambridge, MA (US);

Inventors:

Kiran Reddy, Boston, MA (US);

Gabriel Martinez Botella, Wayland, MA (US);

Andrew Mark Griffin, L'lle Bizard, CA;

Brian Edward Marron, Ada, MI (US);

Carlos Loya, Cambridge, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4985 (2006.01); C07D 487/04 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61P 25/00 (2018.01);
Abstract

The present invention is directed to, in part, fused heteroaryl compounds of Formula (II-II): and compositions thereof, useful for preventing and/or treating a disease or condition relating to aberrant function of a voltage-gated, sodium ion channel, for example, abnormal late/persistent sodium current. Methods of treating a disease or condition relating to aberrant function of a sodium ion channel including neurological disorders (e.g., Dravet syndrome, epilepsy), pain, and neuromuscular disorders are also provided herein.


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