The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 26, 2023
Filed:
May. 26, 2022
Ganna Bio, Inc., Cambridge, MA (US);
The Children's Medical Center Corporation, Boston, MA (US);
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);
Ryan A. Flynn, Brookline, MA (US);
Brian Goodman, Boston, MA (US);
Ciaran Lawlor, Milton, MA (US);
Namita Bisaria, Somerville, MA (US);
Richard D. Cummings, Brookline, MA (US);
Mohui Wei, Boston, MA (US);
Carolyn R. Bertozzi, Menlo Park, CA (US);
GanNA Bio, Inc., Cambridge, MA (US);
The Children's Medical Center, Boston, MA (US);
Abstract
The present disclosure relates to glycan-modified nucleic acids, including short interfering RNA molecules. The glycan-modified nucleic acids include an oligosaccharide moiety that is bond to the nucleic acid and that contains a multiple antennary complex type N-glycan. The disclosure also relates to pharmaceutical compositions containing such glycan-modified nucleic acids, and methods for making and using such glycan-modified nucleic acids.