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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11766471 B1

PDFFull Text
Date of Patent:
Sep. 26, 2023

Filed:

Dec. 19, 2019

Compositions and methods for induced brown fat differentiation

Applicant:

Dana-farber Cancer Institute, Inc., Boston, MA (US);

Inventors:

Bruce M. Spiegelman, Waban, MA (US);

Shingo Kajimura, San Francisco, CA (US);

Assignee:

Dana-Farber Cancer Institute, Inc., Boston, MA (US);

Attorney:

Foley Hoag LLP

Primary Examiner:

Shin Lin Chen

Int. Cl.
CPC ...
C12N 5/02 (2006.01); C12N 15/85 (2006.01); C07H 21/04 (2006.01); A61K 38/28 (2006.01); C07K 14/47 (2006.01); A61K 31/405 (2006.01); A61K 31/4439 (2006.01); A61K 31/573 (2006.01); C12N 15/63 (2006.01); C12N 5/16 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/28 (2013.01); A61K 31/405 (2013.01); A61K 31/4439 (2013.01); A61K 31/573 (2013.01); C07K 14/4702 (2013.01); A61K 38/00 (2013.01); C07H 21/04 (2013.01); C12N 5/16 (2013.01); C12N 15/63 (2013.01);
Abstract

The invention provides methods and compositions for inducing brown fat cell differentiation through modulation of both Prdm16 and C/EBPβ activity and/or expression. Also provided are methods for preventing or treating obesity or an obesity related disorder in a subject through stimulation of both Prdm16 and C/EBPβ expression and/or activity. Further provided are methods for identifying compounds that are capable of modulating both Prdm16 and C/EBPβ expression and/or activity.

Find Patent Forward Citations

Spiegelman, Bruce. (2023). Compositions and methods for induced brown fat differentiation (U.S. Patent No. 11766471). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11766471

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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