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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 11766455 B1

PDFFull Text
Date of Patent:
Sep. 26, 2023

Filed:

Dec. 14, 2018

Subject-specific tumor inhibiting cells and the use thereof

Applicants:

Ezy Biotech Llc, Wilmington, DE (US);

Adaerata, Limited Partnership, Montréal, CA;

Inventors:

Hua Gu, Westmount, CA;

Gang G Xu, Wilmington, DE (US);

Adeline Gadzinski, Colomb, CA;

Haijun Tong, Shanghai, CN;

Assignees:

EZY Biotech LLC, Wilmington, DE (US);

Adaerata, Limited Patnership, Montreal, CA;

Attorney:

Gann G. Xu

Primary Examiner:

Brian Gangle

Assistant Examiner:

Lakia J Jackson-Tongue

Int. Cl.
CPC ...
A61K 35/17 (2015.01); A61P 35/00 (2006.01); A61K 45/06 (2006.01); C12N 5/0783 (2010.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01);
U.S. Cl.
CPC ...
A61K 35/17 (2013.01); A61K 45/06 (2013.01); A61P 35/00 (2018.01); C12N 5/0636 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 2310/20 (2017.05);
Abstract

This disclosure is directed to a pharmaceutical composition comprises tumor inhibiting cells (TICs) and a method for producing the TICs. The tumor inhibiting cells can be derived from immune cells including T cells, NK cells, or a combination thereof, modified to have inactivated Cbl-b gene alleles and free from Cbl-b bio-function (Cbl-bTICs). The Cbl-bTICs are free from deoxyribonucleic acids exogenous to the immune cells. The immune cells can be isolated using a portable cell isolation and modification device. This disclosure is further directed to a method for treating tumorous conditions in subjects. The pharmaceutical composition can provide a subject-specific tumor treatment.

Find Patent Forward Citations

Gu, Hua. (2023). Subject-specific tumor inhibiting cells and the use thereof (U.S. Patent No. 11766455). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11766455

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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