The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 26, 2023

Filed:

Sep. 26, 2017
Applicant:

Geneheal Biotechnology Co., Ltd., Guangdong, CN;

Inventors:

Wuguang Pan, Guangdong, CN;

Wei Zhu, Guangdong, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/132 (2006.01); A61K 31/155 (2006.01); A61K 38/05 (2006.01); A61K 38/06 (2006.01); A61P 25/00 (2006.01); A61P 35/00 (2006.01); A61K 31/661 (2006.01); A61K 31/513 (2006.01); A61K 31/198 (2006.01); A61K 31/7076 (2006.01); A61K 31/675 (2006.01); A61K 31/415 (2006.01); A61K 31/4402 (2006.01); A61K 31/197 (2006.01); A61K 31/4188 (2006.01); A61K 31/708 (2006.01); C07D 213/66 (2006.01); C07D 213/77 (2006.01); C07D 405/04 (2006.01); C07D 401/04 (2006.01); A61K 31/43 (2006.01); A61P 3/00 (2006.01); C07D 261/04 (2006.01); C07D 207/12 (2006.01); A61P 25/14 (2006.01); A61K 31/33 (2006.01); C07D 473/34 (2006.01); A61K 38/07 (2006.01); A61K 31/397 (2006.01); A61K 31/7072 (2006.01); A61P 25/08 (2006.01); A61K 31/40 (2006.01); A61P 43/00 (2006.01); A61K 31/435 (2006.01);
U.S. Cl.
CPC ...
A61K 31/155 (2013.01); A61K 31/132 (2013.01); A61K 31/197 (2013.01); A61K 31/198 (2013.01); A61K 31/33 (2013.01); A61K 31/397 (2013.01); A61K 31/40 (2013.01); A61K 31/415 (2013.01); A61K 31/4188 (2013.01); A61K 31/43 (2013.01); A61K 31/435 (2013.01); A61K 31/4402 (2013.01); A61K 31/513 (2013.01); A61K 31/661 (2013.01); A61K 31/675 (2013.01); A61K 31/708 (2013.01); A61K 31/7072 (2013.01); A61K 31/7076 (2013.01); A61K 38/05 (2013.01); A61K 38/06 (2013.01); A61K 38/063 (2013.01); A61K 38/07 (2013.01); A61P 3/00 (2018.01); A61P 25/00 (2018.01); A61P 25/08 (2018.01); A61P 25/14 (2018.01); A61P 35/00 (2018.01); A61P 43/00 (2018.01); C07D 207/12 (2013.01); C07D 213/66 (2013.01); C07D 213/77 (2013.01); C07D 261/04 (2013.01); C07D 401/04 (2013.01); C07D 405/04 (2013.01); C07D 473/34 (2013.01);
Abstract

Provided are compounds reducing SAICAR accumulation, and applications. On the basis of existing protein structure data and small molecule structure data, calculations and analysis are performed using software to screen and obtain compounds capable of effectively interfering with PAICS activity, reducing SAICAR synthesis, and ultimately reducing SAICAR accumulation, in order to achieve the goal of treating or improving ADSL deficiency. A better effect in the treatment or improvement of ADSL deficiency is expected from the joint use of at least two of the described compounds.


Find Patent Forward Citations

Pan, Wuguang. (2023). Methods of treating or alleviating adenylosuccinatelyase (adsl) deficiency using spermidine or a pharmaceutically acceptable salt of spermidine (U.S. Patent No. 11766412). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11766412

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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