The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 19, 2023
Filed:
Apr. 05, 2022
Applicant:
Curevac SE, Tübingen, DE;
Inventors:
Assignee:
CureVac SE, Tübingen, DE;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/12 (2006.01); C12N 15/85 (2006.01); A61K 39/205 (2006.01); A61K 48/00 (2006.01); A61K 39/00 (2006.01); C12N 15/67 (2006.01); C12N 15/68 (2006.01); A61K 39/145 (2006.01);
U.S. Cl.
CPC ...
C12N 15/67 (2013.01); A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/205 (2013.01); C12N 15/68 (2013.01); C12N 15/85 (2013.01); A61K 48/00 (2013.01); A61K 2039/53 (2013.01); A61K 2039/54 (2013.01); A61K 2039/575 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/16171 (2013.01); C12N 2760/20134 (2013.01); C12N 2760/20171 (2013.01); C12N 2830/50 (2013.01);
Abstract
The invention relates to an artificial nucleic acid molecule or a vector comprising an open reading frame and a 3'-UTR comprising at least two poly(A) sequences. The invention also relates to a method for increasing protein production from an artificial nucleic acid molecule and to the use of a′-UTR for a method for increasing protein production from an artificial nucleic acid molecule. Moreover, the invention concerns the use of the artificial nucleic acid molecule, the vector, the kit or the pharmaceutical composition as a medicament, as a vaccine or in gene therapy.