The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 19, 2023
Filed:
Mar. 22, 2021
Applicant:
Guangdong Cell Biotechnology Co., Ltd., Dongguan, CN;
Inventors:
Assignee:
GUANGDONG CELL BIOTECHNOLOGY CO., LTD., Dongguan, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61P 17/00 (2006.01); A61P 35/00 (2006.01); A61K 8/14 (2006.01); A61K 8/60 (2006.01); A61K 8/98 (2006.01); A61K 9/127 (2006.01); A61K 35/36 (2015.01); A61Q 19/02 (2006.01); C12N 5/071 (2010.01); C12N 15/88 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 8/14 (2013.01); A61K 8/606 (2013.01); A61K 8/985 (2013.01); A61K 9/127 (2013.01); A61K 35/36 (2013.01); A61P 17/00 (2018.01); A61P 35/00 (2018.01); A61Q 19/02 (2013.01); C12N 5/063 (2013.01); C12N 15/88 (2013.01); A61K 2800/86 (2013.01); C12N 2310/141 (2013.01);
Abstract
An application of a transgenic stem cell-derived exosome in preparing a medicament or whitening cosmetic is provided. In the present disclosure, miR-27b-3p is transfected into an epidermal stem cell, and a transgenic stem cell-derived exosome is harvested. It is experimentally verified that the exosome can inhibit the expression of PIK3R3 protein in melanocytes and the proliferation and migration of melanocytes; and safety experiments further demonstrate the safety of the exosome. Therefore, corresponding medicaments or cosmetics prepared from the exosome have excellent medicinal and cosmetic application prospects.