The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2023

Filed:

Feb. 19, 2020
Applicant:

Julius-maximilians-universität Würzburg, Würzburg, DE;

Inventors:

Jörg Wischhusen, Würzburg, DE;

Markus Junker, Würzburg, DE;

Tina Schäfer, Würzburg, DE;

Dirk Pühringer, Rimpar, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 16/22 (2006.01); C12N 5/10 (2006.01); C12N 15/63 (2006.01); C12N 15/11 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/22 (2013.01); A61K 39/395 (2013.01); A61K 39/3955 (2013.01); A61K 39/39533 (2013.01); A61K 2039/505 (2013.01); A61P 35/00 (2018.01); C07K 2317/24 (2013.01); C07K 2317/34 (2013.01); C07K 2317/565 (2013.01); C07K 2317/73 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01); C12N 5/10 (2013.01); C12N 15/11 (2013.01); C12N 15/63 (2013.01);
Abstract

The present invention relates to monoclonal anti-human-GDF-15 antibodies. The antibodies include chimeric antibodies and humanized antibodies. The invention also relates to monoclonal anti-human-GDF-15 antibodies including murine anti bodies, chimeric antibodies and humanized antibodies for use in methods for the treatment of cancer cachexia and also for the treatment of cancer. The invention also provides pharmaceutical compositions, kits, methods and uses and cell lines capable of producing the monoclonal antibodies of the invention.


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