The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 19, 2023

Filed:

Aug. 12, 2021
Applicant:

Aligos Therapeutics, Inc., South San Francisco, CA (US);

Inventors:

Tongfei Wu, Boortmeerbeek, BE;

Pierre Jean-Marie Bernard Raboisson, Wavre, BE;

Francois Gonzalvez, Antwerp, BE;

Antitsa Dimitrova Stoycheva, Half Moon Bay, CA (US);

Jerome Deval, Pacifica, CA (US);

Cheng Liu, Burlingame, CA (US);

Qingling Zhang, Emerald Hills, CA (US);

Assignee:

Aligos Therapeutics, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/10 (2006.01); C07D 401/14 (2006.01); C07D 471/04 (2006.01); C07D 491/048 (2006.01); C07D 491/107 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/10 (2013.01); C07D 401/14 (2013.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01); C07D 491/107 (2013.01); C07D 519/00 (2013.01);
Abstract

The present disclosure related to compounds that can be useful as inhibitors of PD-1, PD-L1 or the PD-1/PD-L1 interaction. Also disclosed herein are pharmaceutical compositions of that can include a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and uses of or methods of using a compound of Formula (I), or a pharmaceutically acceptable salt thereof, for the treatment of PD-L1 related diseases including but not limited to liver diseases, cancer, hepatocellular carcinoma, viral diseases, or hepatitis B.


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