The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 19, 2023
Filed:
Dec. 15, 2017
Applicants:
LI LI, Shanghai, CN;
Xia Peng, Shanghai, CN;
Guogang Xie, Shanghai, CN;
Inventors:
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61P 37/06 (2006.01); A61P 37/08 (2006.01); A61K 35/15 (2015.01); C12N 5/0787 (2010.01); C12N 5/077 (2010.01);
U.S. Cl.
CPC ...
A61K 9/1271 (2013.01); A61K 9/1277 (2013.01); A61K 35/15 (2013.01); A61P 37/06 (2018.01); A61P 37/08 (2018.01); C12N 5/0642 (2013.01); C12N 5/0652 (2013.01);
Abstract
Provided are an exosome preparation formed by secretion by a mast cell cultured in vitro, a preparation method of an exosome therein, an exosome containing FcεRI protein on an outer surface thereof and in a substantially unbound state, and uses of the exosome preparation or exosome in a method for inhibiting mast cell activation in vitro and in preparing a drug for treating an IgE-mediated disease.