The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2023

Filed:

Nov. 02, 2020
Applicant:

Seven Bridges Genomics Inc., Charlestown, MA (US);

Inventor:

Deniz Kural, Charlestown, MA (US);

Assignee:

Seven Bridges Genomics Inc., Charlestown, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G16B 30/10 (2019.01); G16B 30/00 (2019.01); G16B 45/00 (2019.01); C12Q 1/6869 (2018.01); C12Q 1/6883 (2018.01); G16B 30/20 (2019.01);
U.S. Cl.
CPC ...
G16B 30/10 (2019.02); C12Q 1/6869 (2013.01); C12Q 1/6883 (2013.01); G16B 30/00 (2019.02); G16B 30/20 (2019.02); G16B 45/00 (2019.02); C12Q 2521/301 (2013.01);
Abstract

The invention provides methods for comparing one set of genetic sequences to another without discarding any information within either set. A set of genetic sequences is represented using a directed acyclic graph (DAG) avoiding any unwarranted reduction to a linear data structure. The invention provides a way to align one sequence DAG to another to produce an alignment that can itself be stored as a DAG. DAG-to-DAG alignment is a natural choice wherever a set of genomic information consisting of more than one string needs to be compared to any non-linear reference. For example, a subpopulation DAG could be compared to a population DAG in order to compare the genetic features of that subpopulation to those of the population.


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