The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2023
Filed:
Feb. 03, 2020
Applicant:
Bio-rad Laboratories, Inc., Hercules, CA (US);
Inventors:
Darren Roy Link, Lexington, MA (US);
Michael L. Samuels, Windham, NH (US);
Assignee:
BIO-RAD LABORATORIES, INC., Hercules, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01); G01N 21/64 (2006.01); B01J 19/00 (2006.01); C40B 40/04 (2006.01); C40B 50/08 (2006.01); C40B 60/10 (2006.01); G01N 33/50 (2006.01); C12Q 1/6851 (2018.01); B01F 23/41 (2022.01); B01F 25/433 (2022.01); B01F 33/3011 (2022.01); C12Q 1/25 (2006.01); C12Q 1/6804 (2018.01); C12Q 1/6818 (2018.01); C12Q 1/6827 (2018.01); G01N 33/542 (2006.01); G01N 33/573 (2006.01); G01N 33/58 (2006.01); B01L 7/00 (2006.01);
U.S. Cl.
CPC ...
G01N 21/6445 (2013.01); B01F 23/41 (2022.01); B01F 25/433 (2022.01); B01F 25/4336 (2022.01); B01F 33/3011 (2022.01); B01J 19/0046 (2013.01); B01L 3/502761 (2013.01); C12Q 1/25 (2013.01); C12Q 1/6804 (2013.01); C12Q 1/6818 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6851 (2013.01); C40B 40/04 (2013.01); C40B 50/08 (2013.01); C40B 60/10 (2013.01); G01N 33/5008 (2013.01); G01N 33/542 (2013.01); G01N 33/573 (2013.01); G01N 33/582 (2013.01); B01J 2219/0059 (2013.01); B01J 2219/0065 (2013.01); B01J 2219/0072 (2013.01); B01J 2219/0074 (2013.01); B01J 2219/00286 (2013.01); B01J 2219/00351 (2013.01); B01J 2219/00418 (2013.01); B01J 2219/00479 (2013.01); B01J 2219/00576 (2013.01); B01J 2219/00585 (2013.01); B01J 2219/00592 (2013.01); B01J 2219/00599 (2013.01); B01J 2219/00657 (2013.01); B01J 2219/00664 (2013.01); B01J 2219/00702 (2013.01); B01J 2219/00722 (2013.01); B01J 2219/00743 (2013.01); B01L 7/52 (2013.01); B01L 2200/027 (2013.01); B01L 2300/0636 (2013.01); B01L 2300/0645 (2013.01); B01L 2300/0654 (2013.01); B01L 2300/0681 (2013.01); B01L 2300/0864 (2013.01); B01L 2300/0867 (2013.01); B01L 2400/0415 (2013.01); B01L 2400/0487 (2013.01); G01N 21/6428 (2013.01); G01N 2500/00 (2013.01);
Abstract
The invention generally relates to methods for quantifying an amount of enzyme molecules. Systems and methods of the invention are provided for measuring an amount of target by forming a plurality of fluid partitions, a subset of which include the target, performing an enzyme-catalyzed reaction in the subset, and detecting the number of partitions in the sunset. The amount of target can be determined based on the detected number.