The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2023

Filed:

Jul. 13, 2022
Applicant:

Abs Global, Inc., DeForest, WI (US);

Inventors:

Frederick Savage, DeForest, WI (US);

David Appleyard, DeForest, WI (US);

Zheng Xia, DeForest, WI (US);

Matthew Ebersole, DeForest, WI (US);

Daniel McAda, DeForest, WI (US);

Assignee:

ABS Global, Inc., DeForest, WI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/14 (2006.01); C12N 5/00 (2006.01); G01N 21/64 (2006.01); G02B 21/16 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0093 (2013.01); G01N 15/147 (2013.01); G01N 21/6456 (2013.01); G02B 21/16 (2013.01); G01N 2021/646 (2013.01);
Abstract

A method and related apparatus for confirming whether a kill laser successfully destroys an undesired population of cells includes introducing fluorescent dye into cells, exciting the cells with a detection laser or a light emitting diode to cause the cell to fluoresce for a first time, measuring the amount of fluorescence in the cells with a detector capable of emitting a detection pulse, classifying the cells via embedded processing as undesired or desired cells based on the amount of fluorescence, firing a kill beam with a kill laser at any undesired cells, measuring the amount of fluorescence in the cells a second time to determine whether a fluorescent event was generated from the kill beam striking the cells, and providing feedback to an operator of the kill laser as to whether any fluorescent events were generated from the kill beam striking the cells.


Find Patent Forward Citations

Loading…