The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2023
Filed:
Oct. 09, 2018
Applicant:
Alpine Immune Sciences, Inc., Seattle, WA (US);
Inventors:
Lawrence Evans, Seattle, WA (US);
Joseph L. Kuijper, Seattle, WA (US);
Ryan Swanson, Seattle, WA (US);
Assignee:
Alpine Immune Sciences, Inc., Seattle, WA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/705 (2006.01); A61K 47/65 (2017.01); A61P 19/02 (2006.01); A61K 35/17 (2015.01); C07K 14/725 (2006.01); C12N 5/0783 (2010.01); C12N 15/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70521 (2013.01); A61K 35/17 (2013.01); A61K 47/65 (2017.08); A61P 19/02 (2018.01); C07K 14/7051 (2013.01); C12N 5/0637 (2013.01); C12N 15/00 (2013.01); C07K 2319/02 (2013.01); C07K 2319/03 (2013.01); C07K 2319/30 (2013.01);
Abstract
Provided herein are variant CTLA-4 polypeptides and immunomodulatory proteins and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of disease applications, including for treatment of autoimmune or inflammatory conditions. Compositions and methods for making and using such proteins are provided.