The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2023

Filed:

Oct. 12, 2020
Applicants:

Cytune Pharma, Nantes, FR;

Inserm (Institut National DE LA Santé ET DE LA Recherche Medicale), Paris, FR;

Inventors:

Sebastien Daniel Morisseau, Donges, FR;

Geraldine Teppaz, Nantes, FR;

Yannick Laurent Joseph Jacques, Nantes, FR;

Bruno Gilbert Marc Robert, Valflaunes, FR;

Guy Luc Michel De Martynoff, Mont-St-Guibert, BE;

David Bechard, Saint-Etienne de Montluc, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/54 (2006.01); A61K 38/20 (2006.01); C07K 14/715 (2006.01); C07K 16/32 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/5443 (2013.01); A61K 38/2086 (2013.01); C07K 14/7155 (2013.01); C07K 16/32 (2013.01); A61K 38/00 (2013.01); A61K 2039/505 (2013.01); C07K 16/2887 (2013.01); C07K 16/3084 (2013.01); C07K 2317/24 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C07K 2317/622 (2013.01); C07K 2319/00 (2013.01); C07K 2319/31 (2013.01); C07K 2319/32 (2013.01); C07K 2319/33 (2013.01); C07K 2319/74 (2013.01);
Abstract

The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and (ii) a polypeptide comprising the amino acid sequence of the sushi domain of the interleukin 15R alpha (IL-15Rα) or derivatives thereof; and uses thereof.


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