The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2023

Filed:

Apr. 18, 2022
Applicant:

Zevra Therapeutics, Inc., Celebration, FL (US);

Inventors:

Guochen Chi, Coralville, IA (US);

Sven Guenther, Coralville, IA (US);

Travis Mickle, Kissimmee, FL (US);

Adam Smith, Orlando, FL (US);

Assignee:

Zevra Therapeutics, Inc., Celebration, FL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 213/79 (2006.01); C07D 401/12 (2006.01); C07F 9/10 (2006.01); C07D 265/30 (2006.01); C07D 213/80 (2006.01);
U.S. Cl.
CPC ...
C07D 213/79 (2013.01); C07D 213/80 (2013.01); C07D 265/30 (2013.01); C07D 401/12 (2013.01); C07F 9/10 (2013.01);
Abstract

Disclosed are compounds comprising ketamine (2-(2-chlorophenyl)-2-(methylamino)-cyclohexanone) chemically conjugated to one or more oxoacids, amino acids, polyethylene glycols (PEG or PEO), peptides, phosphates, and/or vitamin compounds, and salts of such compounds. Also disclosed are compositions comprising at least one ketamine compound, or a salt thereof, methods of making such compounds, and methods of using such ketamine compounds and compositions.


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