The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2023

Filed:

Jul. 14, 2020
Applicant:

Nacuity Pharmaceuticals, Inc., Fort Worth, TX (US);

Inventor:

G. Michael Wall, Fort Worth, TX (US);

Assignee:

Nacuity Pharmaceuticals, Inc., Fort Worth, TX (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 323/41 (2006.01); C07C 319/28 (2006.01); A61P 27/02 (2006.01); A61K 9/00 (2006.01); A61K 9/08 (2006.01); C07C 319/12 (2006.01); C07D 277/12 (2006.01); C07C 319/24 (2006.01); A61K 31/00 (2006.01); A61K 31/185 (2006.01); A61K 47/10 (2017.01);
U.S. Cl.
CPC ...
C07C 323/41 (2013.01); A61K 9/0048 (2013.01); A61K 9/08 (2013.01); A61K 31/00 (2013.01); A61K 31/185 (2013.01); A61K 47/10 (2013.01); A61P 27/02 (2018.01); C07C 319/12 (2013.01); C07C 319/24 (2013.01); C07C 319/28 (2013.01); C07D 277/12 (2013.01); C07B 2200/05 (2013.01); C07B 2200/07 (2013.01);
Abstract

The present invention includes pharmaceutical composition comprising (2R,2R')-3,3′-disulfanediyl bis(2-acetamidopropanamide)(diNACA) or D-N-acetyl cysteine amide, or a physiologically acceptable salt thereof, having a deuterium enrichment above the natural abundance of deuterium, and derivatives or solids thereof, and methods of using diNACA to treat eye diseases and other diseases associated with oxidative damage including, e.g., antivenom, beta-thallassemia, cataract, chronic obstructive pulmonary disease, macular degeneration, contrast-induced nephropathy, asthma, lung contusion, methamphetamine-induced oxidative stress, multiple sclerosis, Parkinson's disease, platelet apoptosis, Tardive dyskinesia, Alzheimer disease, HIV-1-associated dementia, mitochondrial diseases, myocardial myopathy, neurodegenerative diseases, pulmonary fibrosis, skin pigmentation, skin in need of rejuventation, antimicrobial infection, Friedreich's ataxia.


Find Patent Forward Citations

Loading…