The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2023
Filed:
Aug. 21, 2018
Applicant:
Case Western Reserve University, Cleveland, OH (US);
Inventors:
Eben Alsberg, Cleveland, OH (US);
Oju Jeon, Cleveland, OH (US);
Assignee:
CASE WESTERN RESERVE UNIVERSITY, Cleveland, OH (US);
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/20 (2006.01); A61L 27/54 (2006.01); A61L 27/44 (2006.01); A61L 27/36 (2006.01); A61L 27/52 (2006.01); A61L 27/58 (2006.01); C08L 89/06 (2006.01); C08L 5/04 (2006.01); C08B 37/00 (2006.01); C08H 1/06 (2006.01); A61L 27/26 (2006.01); A61L 27/38 (2006.01); C08G 65/00 (2006.01);
U.S. Cl.
CPC ...
A61L 27/44 (2013.01); A61L 27/20 (2013.01); A61L 27/26 (2013.01); A61L 27/3608 (2013.01); A61L 27/3834 (2013.01); A61L 27/52 (2013.01); A61L 27/54 (2013.01); A61L 27/58 (2013.01); C08B 37/0084 (2013.01); C08G 65/002 (2013.01); C08H 1/06 (2013.01); C08L 5/04 (2013.01); C08L 89/06 (2013.01); A61L 2300/236 (2013.01); A61L 2300/252 (2013.01); A61L 2300/412 (2013.01); A61L 2300/414 (2013.01); A61L 2400/16 (2013.01); A61L 2430/40 (2013.01); C08L 2205/04 (2013.01); C08L 2312/00 (2013.01);
Abstract
A method for forming a bioactive agent spatially patterned includes providing a photocrosslinkable hydrogel that includes a photocrosslinkable base polymer, photocrosslinkable bioactive agent coupling polymer macromers, and at least one bioactive agent that couples to the photocrosslinkable bioactive agent coupling polymer macromer, an selectively exposing discrete portions of the photocrosslinkable hydrogel to actinic radiation effective to initiate cross-linking of the base polymer and the bioactive agent coupling polymer macromers at the exposed portions.