The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2023
Filed:
Sep. 09, 2020
Applicant:
Duke University, Durham, NC (US);
Inventors:
Angus Hucknall, Durham, NC (US);
Ashutosh Chilkoti, Durham, NC (US);
Daniel Joh, Durham, NC (US);
Nancy J. Ganson, Durham, NC (US);
Yizhi Qi, Durham, NC (US);
Michael S. Hershfield, Durham, NC (US);
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/58 (2017.01); A61K 47/59 (2017.01); C08L 71/08 (2006.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
A61K 47/58 (2017.08); A61K 47/59 (2017.08); A61K 47/641 (2017.08); C08L 71/08 (2013.01); C08L 2203/02 (2013.01);
Abstract
Disclosed herein are compositions and methods for reducing the antigenicity of molecules. The antigenicity of a molecule may be reduced or eliminated by conjugating at least one branched polymer to the molecule to form a molecule-polymer conjugate. The branched polymer may include a backbone and a plurality of side chains, each side chain covalently attached to the backbone.