The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2023

Filed:

Nov. 04, 2022
Applicant:

Jinis Co., Ltd., Jeollabuk-do, KR;

Inventors:

Hyeon Jin Kim, Jeollabuk-do, KR;

Seong Tshool Hong, Jeonju-si, KR;

Hea Jong Chung, Jeonju-si, KR;

Heui Kwan Lee, Jeonju-si, KR;

Hea Guk Cho, Gwangju, KR;

Jae Gak Yu, Chungcheongnam-do, KR;

Assignee:

JINIS CO., LTD., Wanju-gun, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2020.01); A61K 38/40 (2006.01); A61K 33/06 (2006.01); A61K 33/24 (2019.01); A61K 33/26 (2006.01); A61K 45/06 (2006.01); A61N 5/02 (2006.01); A61N 5/06 (2006.01); A61N 5/10 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0052 (2013.01); A61K 33/06 (2013.01); A61K 33/24 (2013.01); A61K 33/26 (2013.01); A61K 38/40 (2013.01); A61K 45/06 (2013.01); A61N 5/02 (2013.01); A61N 5/062 (2013.01); A61N 2005/0659 (2013.01); A61N 2005/0661 (2013.01); A61N 2005/0662 (2013.01); A61N 2005/1098 (2013.01);
Abstract

Disclosed are a sensitizing composition for thermal cancer therapy using electromagnetic waves and a method of treating cancer using the composition. The sensitizing composition includes a metal ion, a metal ion-bound material, metal ion-noncovalently bound apotransferrin (transferrin), or a metal ion-noncovalently bound apotransferrin derivative. The sensitizing composition enables selective delivery of the metal ion to tumorous tissue when administered in vivo, and thus the generation of heat in tumorous tissue in which the metal ion accumulates is increased upon thermal cancer therapy using electromagnetic waves, thereby maximizing efficacy of thermal cancer therapy using electromagnetic waves in treating cancer. Thermal therapy using the sensitizing composition effectively treats cancer without pain or side effects and is thus expected to be widely useful in anticancer treatment as monotherapy, and/or in combination with chemotherapy, radiation therapy, or a combination thereof, ultimately increases the potential to cure cancer.


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