The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2023
Filed:
Mar. 06, 2019
Athenex HK Innovative Limited, Hong Kong, HK;
Johnson Yiu-Nam Lau, Houston, TX (US);
Alissa Rae Verone-Boyle, Kenmore, NY (US);
Chun-Ho Wong, Shatin, HK;
Yahao Bu, Williamsville, NY (US);
Murray John Cutler, Fort Erie, CA;
Krista Elizabeth Belko, Clarence Center, NY (US);
Min-Fun Rudolf Kwan, Summit, NJ (US);
Athenex HK Innovative Limited, Sha Tin, HK;
Abstract
Compositions and methods are provided that are effective in treating skin hyperproliferative disorders. These include a topical pharmaceutical preparation that includes a compound that has two or more of a SRC-kinase inhibiting activity, a tubulin polymerization inhibiting activity, an activity that arrests the cell cycle at G2/M, and an activity that induces apoptosis. The compound KX01 is provided as an example of such a compound. The topical pharmaceutical preparation further includes a vitamin D derivative or a retinoid, where the combination provides a synergistic effect. Use of the topical pharmaceutical preparation can be combined with exposure to blue, UVA, or UVB light, which provides a synergistic effect.