The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2023
Filed:
Nov. 03, 2022
Southern Research Institute, Birmingham, AL (US);
The Uab Research Foundation, Birmingham, AL (US);
Corinne E. Augelli-Szafran, Homewood, AL (US);
Omar Moukha-Chafiq, Birmingham, AL (US);
Mark J. Suto, Homewood, AL (US);
Anath Shalev, Mountain Brook, AL (US);
Lance Thielen, Lenexa, KS (US);
Junqin Chen, Vestavia Hills, AL (US);
Gu Jing, Vestavia Hills, AL (US);
SOUTHERN RESEARCH INSTITUTE, Birmingham, AL (US);
THE UAB RESEARCH FOUNDATION, Birmingham, AL (US);
Abstract
In one aspect, compounds and compositions that inhibit TXNIP expression and/or that lower hepatic glucose production and methods of identifying, making, and using same are disclosed. The disclosed compounds and compositions can be useful for disorders associated with elevated TXNIP and/or elevated glucagon levels such as, for example, diabetes and associated disorders. Further provided are methods for treating hyperlipidemia or fatty liver disease, optionally associated with elevated TXNIP and/or elevated glucagon levels. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.