The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2023
Filed:
Nov. 26, 2014
Applicant:
The State of Israel Ministry of Agriculture & Rural Development, Argicultural Research Organization, (Aro) (Volcani Center), Rishon Le Zion, IL;
Inventors:
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/352 (2006.01); A61K 36/28 (2006.01); A61K 31/343 (2006.01);
U.S. Cl.
CPC ...
A61K 31/352 (2013.01); A61K 31/343 (2013.01); A61K 36/28 (2013.01);
Abstract
The invention relates to 3,5,4'-trihydroxy-6,7,3′-trimethoxyflavone (TIF) and achillolid A in prevention or treatment of Alzheimer's disease as well as other neurodegenerative diseases such as Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), ischemia, immunodeficiency virus-1 (HTV-1)-associated dementia, Lewy body associated dementia, traumatic brain injury (TBI), glioma, epilepsy. Huntington's disease, multiple sclerosis, glaucoma and schizophrenia where neuroinflammation, oxidative stress, glutamate toxicity and amyloid beta toxicity are part of the pathophysiology.