The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 12, 2023
Filed:
Sep. 08, 2021
Applicants:
University of Central Florida Research Foundation, Inc., Orlando, FL (US);
Trustees of Boston University, Boston, MA (US);
Inventors:
Otto Phanstiel, IV, Orlando, FL (US);
John Connor, Boston, MA (US);
Assignees:
University of Central Florida Research Foundation, Inc., Orlando, FL (US);
Boston University, Boston, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/132 (2006.01); A61K 31/198 (2006.01); A61K 31/13 (2006.01); A61K 31/155 (2006.01); A61K 31/404 (2006.01); A61K 31/16 (2006.01); A61P 31/12 (2006.01); A61K 31/4706 (2006.01); A61K 31/522 (2006.01); A61K 31/4985 (2006.01); A61K 31/505 (2006.01); A61K 31/513 (2006.01); A61K 31/675 (2006.01);
U.S. Cl.
CPC ...
A61K 31/132 (2013.01); A61K 31/13 (2013.01); A61K 31/155 (2013.01); A61K 31/16 (2013.01); A61K 31/198 (2013.01); A61K 31/404 (2013.01); A61K 31/4706 (2013.01); A61K 31/4985 (2013.01); A61K 31/505 (2013.01); A61K 31/513 (2013.01); A61K 31/522 (2013.01); A61K 31/675 (2013.01); A61P 31/12 (2018.01);
Abstract
Disclosed herein are polyamine transport inhibitors (PTI) and methods of use as antivirals. Disclosed PTI compounds are useful as treatments for viral infections or can be used as prophylactic agents that protect high risk individuals from becoming infected by the virus. The disclosed PTI compounds can be used alone or in combination with other agents (or other antivirals) to improve patient outcomes such as DFMO (or Remdesivir).