The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 12, 2023

Filed:

Aug. 28, 2019
Applicant:

Purdue Research Foundation, West Lafayette, IN (US);

Inventors:

Brian Zahler Bentz, Albuquerque, NM (US);

Kevin J. Webb, West Lafayette, IN (US);

Dergan Lin, West Lafayette, IN (US);

Justin Alexander Patel, West Lafayette, IN (US);

Assignee:

Purdue Research Foundation, West Lafayette, IN (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 90/00 (2016.01);
U.S. Cl.
CPC ...
A61B 5/4064 (2013.01); A61B 5/0062 (2013.01); A61B 5/0071 (2013.01); A61B 5/0077 (2013.01); A61B 90/37 (2016.02); A61B 2090/371 (2016.02);
Abstract

A system for spatially mapping neurons in brain tissue is disclosed which includes a source of light configured to be shone on a subject at a first wavelength causing emission of light at a second wavelength from generating calcium when one or more neurons are firing, an optical filter configured to allow passage of light having the second wavelength, an image capture device configured to capture images of the brain tissue at the second wavelength, and a processor with software configured to establish a spatial model for localizing one or more neurons where captured images are used to iteratively adjust parameters of the model to thereby minimize error between generated and captured images.


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