The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2023

Filed:

May. 04, 2021
Applicant:

Waters Technologies Corporation, Milford, MA (US);

Inventors:

Michael O. Fogwill, Uxbridge, MA (US);

Sylvain Gilles Cormier, Mendon, MA (US);

Thomas Swann, Hopedale, MA (US);

Francis Patrick Tracey, Medway, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 30/46 (2006.01); G01N 30/02 (2006.01);
U.S. Cl.
CPC ...
G01N 30/468 (2013.01); G01N 30/463 (2013.01); G01N 2030/027 (2013.01);
Abstract

Multidimensional liquid chromatography (MDLC) systems include valve configurations that enable a flow containing analytes in the eluent of a first dimension liquid chromatography system to be modulated such that the analytes can be captured in fluidic loops and subsequently provided to a second dimension liquid chromatography system. Optionally, a single detector is used for both first and second dimensions. In addition, the systems can enable dilution of the analytes and enable incompatible mobile phases and mobile phase flow rates to be used in the first and second dimensions.


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