The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2023

Filed:

Jun. 16, 2021
Applicant:

University of Central Florida Research Foundation, Inc., Orlando, FL (US);

Inventors:

Swaminathan Rajaraman, Winter Park, FL (US);

Avra Kundu, Orlando, FL (US);

Adam Rozman, Oviedo, FL (US);

Jorge Manrique Castro, Orlando, FL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B29C 64/124 (2017.01); C12M 1/34 (2006.01); C12M 1/00 (2006.01); C12M 1/32 (2006.01); B33Y 10/00 (2015.01); B33Y 80/00 (2015.01); C12M 3/06 (2006.01); C12M 1/12 (2006.01); C12M 1/42 (2006.01); G01N 33/483 (2006.01); G01N 35/00 (2006.01); C12M 1/26 (2006.01);
U.S. Cl.
CPC ...
C12M 41/46 (2013.01); B29C 64/124 (2017.08); B33Y 10/00 (2014.12); B33Y 80/00 (2014.12); C12M 23/12 (2013.01); C12M 23/16 (2013.01); C12M 23/22 (2013.01); C12M 25/08 (2013.01); C12M 35/02 (2013.01); C12M 33/00 (2013.01); G01N 33/4836 (2013.01); G01N 2035/00158 (2013.01);
Abstract

A method of forming a high-throughput, three-dimensional (3D) microelectrode array for in vitro electrophysiological applications includes 3D printing a well plate having a top face and bottom face. A plurality of culture well each includes a plurality of 3D printed, vertical microchannels and microtroughs communicating with the microchannels. The microtroughs and the microchannels are filled with a conductive paste to form self-isolated microelectrodes in each of the culture wells and conductive traces that communicate with the self-isolated microelectrodes.


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