The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 05, 2023
Filed:
Jul. 14, 2021
University of Pittsburgh-of the Commonwealth System of Higher Education, Pittsburgh, PA (US);
Cedars-sinai Medical Center, Los Angeles, CA (US);
Ivet Bahar, Wexford, PA (US);
Hongying Cheng, Pittsburgh, PA (US);
She Zhang, Pittsburgh, PA (US);
Rebecca Porritt, Sherman Oaks, CA (US);
Moshe Arditi, Encino, CA (US);
University of Pittsburgh—Of The Commonwealth System of Higher Education, Pittsburgh, PA (US);
Cedars-Sinai Medical Center, Los Angeles, CA (US);
Abstract
Provided herein are methods of treating a COVID-19 infection in a subject, comprising administering to the subject an effective amount of a composition that reduces the superantigen character of SARS-CoV-2 Spike protein. In some embodiments, the compositions are mimetic peptides of the superantigen region. In some embodiments, the compositions are humanized antibodies, such as humanized mAb 6D3, that bind to the superantigen region.