The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2023

Filed:

Apr. 02, 2020
Applicant:

Curevac Manufacturing Gmbh, Tübingen, DE;

Inventors:

Thorsten Mutzke, Reutlingen, DE;

Markus Kreuz, Kohlberg, DE;

Stefanie Sewing, Tübingen, DE;

Fabian Johannes Eber, Stuttgart, DE;

Wenke Wagner, Reutlingen, DE;

Michael Sonntag, Tübingen, DE;

Michael Wiggenhorn, Munich, DE;

Katharina Kolland, Augsburg, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/145 (2006.01); A61K 48/00 (2006.01); A61K 47/64 (2017.01); A61K 9/51 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/145 (2013.01); A61K 9/5169 (2013.01); A61K 9/5192 (2013.01); A61K 39/12 (2013.01); A61K 47/646 (2017.08); A61K 47/6455 (2017.08); A61K 2039/55555 (2013.01); C12N 2760/16134 (2013.01);
Abstract

The present invention relates to a method for producing a liquid composition comprising a nanoparticle comprising at least one RNA and at least one cationic or polycationic compound, advantageously on a large scale suitable for pharmaceutical applications. The present invention further concerns the use of the inventive method in the manufacture of a medicament or a vaccine. Furthermore, the invention relates to compositions containing the RNA-comprising nanoparticle, and to pharmaceutical compositions comprising the same.


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