The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2023

Filed:

Mar. 26, 2019
Applicants:

Ustav Organicke Chemie a Biochemie Av Cr, V.v.i., Prague, CZ;

Masarykova Univerzita, Brno, CZ;

Fakultni Nemocnice U Sv. Anny V Brne, Brno, CZ;

Inventors:

Petr Cigler, Prague, CZ;

Lukas Balek, Klimkovice, CZ;

Jan Havlik, Znojmo, CZ;

Pavel Krejci, Brno, CZ;

Lukas Trantirek, Brno, CZ;

Silvie Trantirkova, Brno, CZ;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 33/44 (2006.01); A61K 9/14 (2006.01); A61K 45/06 (2006.01); C07K 14/50 (2006.01);
U.S. Cl.
CPC ...
A61K 33/44 (2013.01); A61K 9/14 (2013.01); A61K 45/06 (2013.01); C07K 14/50 (2013.01);
Abstract

Nanodiamonds having a positive ζ-potential of at least 1 mV for use in sequestration of at least one FGF family member in organisms in vivo and in vitro. It has been found that nanodiamonds with a positive ζ-potential show an extremely strong and selective binding to FGF family members, thus leading to their usability in the treatment of diseases related to aberrant FGF-FGFR signalling and/or interaction.


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