The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2023

Filed:

Jun. 29, 2021
Applicants:

Emory University, Atlanta, GA (US);

The United States Government As Represented BY the Department of Veterans Affairs, Washington, DC (US);

Inventors:

Christina Gavegnano, Decatur, GA (US);

Raymond F Schinazi, Miami, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/66 (2006.01); A61K 31/70 (2006.01); A61K 45/06 (2006.01); A61K 31/7072 (2006.01); A61K 31/4045 (2006.01); A61K 31/52 (2006.01); A61K 31/536 (2006.01); A61K 31/513 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/4045 (2013.01); A61K 31/513 (2013.01); A61K 31/52 (2013.01); A61K 31/536 (2013.01); A61K 31/66 (2013.01); A61K 31/7072 (2013.01); A61K 45/06 (2013.01); Y02A 50/30 (2018.01);
Abstract

Compounds, compositions, and methods of treatment and prevention of Hepacivirus, Pestivirus, Flavivirus or Alphavirus infection are disclosed. The compounds are pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidine JAK inhibitors. Combinations of these JAK inhibitors and additional antiretroviral compounds, such as NRTI, NNRTI, integrase inhibitors, entry inhibitors, protease inhibitors, and the like, are also disclosed. In one embodiment, the combinations include a combination of adenine, cytosine, thymidine, and guanine nucleoside antiviral agents, optionally in further combination with at least one additional antiviral agent that works via a different mechanism than a nucleoside analog. This combination has the potential to eliminate the presence of Hepacivirus, Pestivirus, Flavivirus or Alphavirus in an infected patient.


Find Patent Forward Citations

Gavegnano, Christina. (2023). Antiviral jak inhibitors useful in treating or preventing retroviral and other viral infections (U.S. Patent No. 11744831). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/11744831

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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