The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2023

Filed:

Sep. 08, 2021
Applicants:

Axial Therapeutics, Inc., Woburn, MA (US);

California Institute of Technology, Pasadena, CA (US);

Inventors:

Timothy Sampson, Los Angeles, CA (US);

Sarkis Mazmanian, Glendale, CA (US);

Anthony Stewart Campbell, Framingham, MA (US);

Assignees:

Axial Therapeutics, Inc., Woburn, MA (US);

California Institute of Technology, Pasadena, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/353 (2006.01); A61P 25/28 (2006.01); A61P 25/16 (2006.01); A61K 31/05 (2006.01); A61K 31/192 (2006.01); A61K 31/216 (2006.01); A61K 31/235 (2006.01); A61K 31/465 (2006.01); A61K 31/522 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/353 (2013.01); A61K 31/05 (2013.01); A61K 31/192 (2013.01); A61K 31/216 (2013.01); A61K 31/235 (2013.01); A61K 31/465 (2013.01); A61K 31/522 (2013.01); A61K 45/06 (2013.01); A61P 25/16 (2018.01); A61P 25/28 (2018.01);
Abstract

The present disclosure provides methods and compositions for the prevention, amelioration, or alleviation of one or more neurological disorders associated with microbially-induced amyloid formation. Methods of inhibiting, ameliorating, reducing the likelihood, delaying the onset of, treating, or preventing an amyloid disorder are disclosed. Methods of identifying compounds capable of inhibiting the formation of microbially-induced amyloid fibrils are disclosed.


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