The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 05, 2023

Filed:

Oct. 14, 2021
Applicant:

Lanzhou University, Lanzhou, CN;

Inventors:

Jianye Dai, Lanzhou, CN;

Zheng Jin, Lanzhou, CN;

Ruyun Ma, Lanzhou, CN;

Yanning Zhu, Lanzhou, CN;

Assignee:

Lanzhou University, Lanzhou, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/231 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/231 (2013.01); A61P 35/00 (2018.01);
Abstract

Some embodiments of the disclosure provide new uses of trans-1,3-dilinolein as medicaments and food. In an embodiment, an application of trans-1,3-dilinolein in the preparation of stomachic tonic and an application thereof include the preparation of medicaments for treating gastric cancer. Cell experiments show that trans-1,3-dilinolein promotes the proliferation of human gastric mucosal epithelial cell line GES-1 under normal oxygen and hypoxic conditions and it has concentration-dependent killing effect on human gastric cancer cell line HGC-27 and killing effect on hypoxic gastric cancer cells. At a concentration of 300 μm and more, trans-1,3-dilinolein kills gastric cancer cells significantly and the killing effect becomes more significant under hypoxic conditions.


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