The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 05, 2023
Filed:
Aug. 31, 2018
Applicant:
Modernatx, Inc., Cambridge, MA (US);
Inventors:
Joseph Schariter, Cambridge, MA (US);
Kimberly Hassett, Cambridge, MA (US);
Mike Smith, Cambridge, MA (US);
Orn Almarsson, Cambridge, MA (US);
Luis Brito, Cambridge, MA (US);
Assignee:
ModernaTX, Inc., Cambridge, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/60 (2017.01); B82Y 5/00 (2011.01); A61K 9/127 (2006.01); A61K 9/19 (2006.01);
U.S. Cl.
CPC ...
A61K 9/19 (2013.01); A61K 47/60 (2017.08); A61K 9/127 (2013.01); A61K 9/1277 (2013.01); B82Y 5/00 (2013.01);
Abstract
The disclosure features novel methods of producing nucleic acid lipid nanoparticle (LNP) compositions employing a modifying agent after formation of a precursor nucleic acid lipid nanoparticle, the produced compositions thereof, and methods involving the nucleic acid lipid nanoparticles useful in the delivery of therapeutics and/or prophylactics, such as a nucleic acid, to mammalian cells or organs to, for example, to regulate polypeptide, protein, or gene expression.