The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 29, 2023

Filed:

Aug. 31, 2018
Applicant:

Sapphire Diagnostics, Llc, San Diego, CA (US);

Inventors:

Andrew Douglas Penman, Birmingham, AL (US);

Marcus Willard Smith, Birmingham, AL (US);

Catalina Valencia, San Diego, CA (US);

Sergei A Svarovsky, San Diego, CA (US);

Assignee:

ADVANCED TEAR DIAGNOSTICS, LLC., Birmingham, AL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 27/327 (2006.01); G01N 33/574 (2006.01); A61B 5/1486 (2006.01); G01N 33/543 (2006.01); A61B 5/145 (2006.01); G01N 27/02 (2006.01); G01N 27/22 (2006.01);
U.S. Cl.
CPC ...
G01N 27/327 (2013.01); A61B 5/1486 (2013.01); A61B 5/14532 (2013.01); G01N 27/02 (2013.01); G01N 27/026 (2013.01); G01N 27/22 (2013.01); G01N 27/3275 (2013.01); G01N 33/5438 (2013.01); G01N 33/57415 (2013.01); G01N 33/57488 (2013.01);
Abstract

The presence of biomarkers or other analytes can be detected in the bodily fluid using Electrochemical Impedance Spectroscopy (EIS) or Electrochemical Capacitance Spectroscopy (ECS) in devices, such as handheld point-of-care devices. The devices, as well as systems and methods, utilize using Electrochemical Impedance Spectroscopy (EIS) or Electrochemical Capacitance Spectroscopy (EIS) in combination with an antibody or other target-capturing molecule on a working electrode. Imaginary impedance or phase shift, as well as background subtraction, also may be utilized.


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