The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 29, 2023
Filed:
Aug. 10, 2018
Applicant:
Atila Biosystems Incorporated, Palo Alto, CA (US);
Inventors:
Youxiang Wang, Palo Alto, CA (US);
Zhijie Yang, Palo Alto, CA (US);
Xin Chen, Palo Alto, CA (US);
Yu Zhao, Palo Alto, CA (US);
Rong Wang, Palo Alto, CA (US);
Assignee:
ATILA BIOSYSTEMS INCORPORATED, Palo Alto, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6858 (2018.01); C12Q 1/6853 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6858 (2013.01); C12Q 1/6853 (2013.01); C12Q 2523/125 (2013.01); C12Q 2525/185 (2013.01); C12Q 2537/16 (2013.01); C12Q 2563/159 (2013.01);
Abstract
The invention provides methods of digital amplification using primers of limited nucleotide composition. Limited nucleotide composition means that the primers are underrepresented in at least one nucleotide type. Such primers have much reduced capacity to prime from each other or to extend initiated by mispriming from other than at their intended primer binding sites in a target nucleic acid.